Are there instructions on how to use Intune?

Intune is constantly being updated with new features and patches, so Microsoft's official documentation is the best resource for any Intune information.

Overview of Intune

Common Tasks

Assign Applications

Autopilot

Configure Device Settings

Configure Compliance Policies

Create Applications (Please Start all of your applications with your department's acronym)

Create Groups*

Defender for Endpoint

Device Enrollment

Protect Devices

Remotely Manage Devices

* Dynamic groups are not available at this time but can be requested by selecting "New Dynamic Group (Intune)" when filling out this form.
 
Feel free to take a look at what could be coming soon to Intune while you are navigating through all of the documentation:

New Features in Development